AZD8359 Datasheet DC Chemicals

Description	AZD8359 is a STEAP2-targeting T-cell engager. STEAP2 is a highly specific prostate-associated surface antigen that is strongly expressed across all stages of prostate adenocarcinoma. Built on AstraZeneca’s TITAN platform, AZD8359 is engineered to bias activity toward CD8+ T cells. Its "2+1" antibody format favors CD8+ over CD4+ T cells, preserving tumor cell killing while reducing the risk of cytokine release syndrome and off-target toxicity.
Cat.No	DC68049
Name	AZD8359

Chemical Properties

CAS
Formula
MW
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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