EPI-326 Datasheet DC Chemicals
Description This therapeutic candidate, known as EpiTAC, is a tissue-selective bispecific antibody developed for EGFR-driven cancers. It works by binding to ITGB6 (integrin subunit beta-6), which promotes the degradation of both wild-type and mutant forms of EGFR specifically within tumor tissues. This triggers lysosome-mediated protein breakdown, potentially expanding the reach of EGFR-targeted therapy beyond currently defined mutation-restricted patient populations.
Cat.No DC68050
Name EPI-326

Chemical Properties

CAS
Formula
MW
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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