HGT5001 Datasheet DC Chemicals

Description	HGT5001, disclosed in patent US 2026/0125339 A1 by Translate Bio (now part of Sanofi), is a novel ionizable cationic lipid optimized for mRNA delivery. It enables efficient LNP assembly, high mRNA encapsulation, potent endosomal escape, and exceptional in vivo protein expression, with demonstrated efficacy in therapeutic mRNA applications, low toxicity, and favorable biocompatibility, making it a leading candidate for advanced mRNA therapeutics.
Cat.No	DC68162
Name	HGT5001

Chemical Properties

CAS
Formula
MW
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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