JH295 hydrate Datasheet DC Chemicals

Description	JH295 hydrate is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM. JH295 hydrate inhibits cellular Nek2 via alkylation of Cys22. JH295 hydrate is inactive against the mitotic kinases, Cdk1, Aurora B or Plk1, and does not perturb bipolar spindle assembly or the spindle assembly checkpoint.
Cat.No	DC40235
Name	JH295 hydrate

Chemical Properties

CAS
Formula	C18H18N4O3
MW	338.36
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

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