S 297995 Datasheet DC Chemicals
Description Naldemedine, also known as S 297995, is a peripherally-selective μ-opioid receptor antagonist under development by Shionogi for the treatment of opioid-induced adverse effects including constipation, nausea, and vomiting. Clinical studies have thus far found it to possess statistically significant effectiveness for these indications and to be generally well-tolerated with predominantly mild to moderate gastrointestinal side effects. No effects indicative of central opioid withdrawal or impact on the analgesic or mydriatic effects of co-administered opioids have been observed.
Cat.No DC32049
Name S 297995

Chemical Properties

CAS 916072-89-4
Formula C32H34N4O6
MW 570.64
Storage

References

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