TD-198946 Datasheet DC Chemicals

Description	TD-198946(TD198946 ) is a small molecule stimulator of chondrogenesis; promotes chondrocyte differentiation.
Cat.No	DC10118
Name	TD-198946

Chemical Properties

CAS	364762-86-7
Formula	C27H22N4O3S
MW	482.1
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Yano F, et al. A novel disease-modifying osteoarthritis drug candidate targeting Runx1. Ann Rheum Dis. 2013 May;72(5):748-53. [2]. Yano F, et al. Disease-modifying effects of TD-198946 on progressed osteoarthritis in a mouse model. Ann Rheum Dis. 2014 Nov;73(11):2062-4. [3]. Yano F, et al. Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration. Biomaterials. 2013 Jul;34(22):5581-7.

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