IACS-56676 Datasheet DC Chemicals

Description	IACS-56676 is a selective NRASG12D inhibitor with a target Kd of 0.031 μM. IACS-56676 stabilizes the p-loop, maintains key interactions with Asp12, Gly60 and Asp69, and achieves selectivity over wild-type KRAS through substitution targeting Leu95. IACS-56676 can be used for research on melanoma, hematologic malignancies and thyroid cancer.
Cat.No	DC80825
Name	IACS-56676

Chemical Properties

CAS	3093661-88-9
Formula	C24H21CLN4O3S
MW	480.97
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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