BION106 Datasheet DC Chemicals

Description	BION106 is a dihydrofolate reductasethymidylate synthase (DHFR-TS) PROTAC degrader. BION106 exhibits extremely strong anti-malarial activity with a Ki and toxicity of 2.68 nM and 0.2 μM against Plasmodium falciparum, and > 100 μM and 44.2 μM in mammalian cells. BION106 can be used for the study of antimalarial parasites.
Cat.No	DC78689
Name	BION106

Chemical Properties

CAS	3077918-44-3
Formula	C57H69CL2F2N9O9
MW	1133.12
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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