Meayamycin B Datasheet DC Chemicals

Description	Meayamycin B ((+)-Meayamycin B) is a potent SF3B1 inhibitor. Meayamycin B upregulates the proapoptotic Mcl-1S and downregulates Mcl-1L at the pre-mRNA splicing level. Meayamycin B does not regulate the alternative splicing of Bcl-x. Meayamycin B and ABT-737 synergistically causes Apoptosis. Meayamycin B exhibits anticancer activity against non-small cell lung cancer.
Cat.No	DC81021
Name	Meayamycin B

Chemical Properties

CAS	1008116-73-1
Formula	C28H26FN5O3S
MW	531.6
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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