Canakinumab Biosimilar（Anti-IL-1b Reference Antibody） Datasheet DC Chemicals
Description Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin.
Cat.No A235
Name Canakinumab Biosimilar（Anti-IL-1b Reference Antibody）

Chemical Properties

CAS 914613-48-2
Synonyms Canakinumab;Anti-Human IL-1B(Canakinumab);Research Grade Canakinumab(DHB95601);Ilaris; ACZ 885
pH value Corresponds to reference standard: PASS
Non-reduced CE-SDS >95%
SEC-HPLC >95%
Isoelectric Point Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality Corresponds to reference standard: PASS
Peptide mapping Corresponds to reference standard: PASS
N-terminal sequence Corresponds to reference standard: PASS

References

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