DBCO-PEG2-Val-Cit-PAB-MMAE Datasheet DC Chemicals

Description	DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The DBCO group is a click chemistry handle which readily reacts with azide groups, while the Val-Cit is a protease-cleavable dipeptide which releases the MMAE warhead into cells via an elimination mechanism.
Cat.No	DC77467
Name	DBCO-PEG2-Val-Cit-PAB-MMAE

Chemical Properties

CAS	2845934-59-8
Formula	C84H120N12O17
MW	1569.92
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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