Dirozalkib Datasheet DC Chemicals

Description	Dirozalkib (Compound 4) is the inhibitor for ALK with an IC50 of 0.9 nM. Dirozalkib exhibits anti-proliferative activity in cancer cells NCI-H3122, Karpas-299 and NCI-H2228 with IC50s of 130.4, 0.71 and 15.11 nM, respectively. Dirozalkib exhibits good pharmacokinetics characteristics with an bioavailbility of 30%~50%.
Cat.No	DC77151
Name	Dirozalkib

Chemical Properties

CAS	1893419-37-8
Formula	C27H32CLN5O4S
MW	558.09
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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