SIAIS001 Datasheet DC Chemicals

Description	SIAIS001 is a potent and orally active PROTAC ALK degrader with a DC50 of 3.9 nM. SIAIS001 induces G1/S phase cell cycle arrest and inhibits proliferation of SR cells (IC50 = 0.9 nM). SIAIS001 can be used for non-small cell lung cancer (NSCLC) and anaplastic large-cell lymphomas (ALCLs) research. (Pink: Anaplastic lymphoma kinase (ALK) ligand ; Blue: TNF Receptor ligand ; Black: linker).
Cat.No	DC81533
Name	SIAIS001

Chemical Properties

CAS	251647-53-7
Formula	C49H56N7O9P
MW	917.98
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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