DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers.
DBCO (diphenylcycloctene) is a cycloalkyne, CAS: 1255942-06-3, chemical formula: C18H16N2O, that can react with azide (-N3) compounds in aqueous solutions through a strain-facilitated 1, 3-dipole cycloaddition reaction, a biological orthogonal reaction also known as a cupr-free click reaction. The reaction has excellent selectivity and biocompatibility, so the complementary reagents can form covalent bonds with functionally rich biological systems. Copper-free click reaction has been a powerful tool for catalyst-free bioconjugation. DBCO reagent has affinity and stability in water-based buffers and can be used to label azide-modified biomolecules with high specificity and reactivity. Active esters modify molecules with primary amines.
