DSPE-PEG-Silane is a surface-active phospholipid PEG derivative that can be used to modify the surfaces of glass, silica particles, and many other materials. DSPE-PEG-Silane is used as a PEG matrix in the preparation of pharmaceutical nanoparticles and can be used to control particle size and stability. It can also be applied to the preparation of biocompatible nanocarriers, such as nanoparticle carriers. Silyl groups are highly reactive to glass, silica, and many other materials. The reaction between alkoxysilane and the surface hydroxyl group makes the phospholipid PEG covalently attached to the surface of the modified material. Non-specific binding on the surface of PEG modified materials.
