DU-14 (PTP1B/TC-PTP PROTAC) Datasheet DC Chemicals

Description	DU-14 (PTP1B/TC-PTP PROTAC) is a potent and selective PTP1B and TC-PTP dual PROTAC degrader. DU-14 (PTP1B/TC-PTP PROTAC) has the IC50 for PTP1B and TC-PTP phosphatase activity of 24.2 nM and 30.1 nM, respectively. DU-14 (PTP1B/TC-PTP PROTAC) enhances IFN-γ signaling, promotes T cell activation, and has anti-tumor activity.
Cat.No	DC77229
Name	DU-14 (PTP1B/TC-PTP PROTAC)

Chemical Properties

CAS	3053413-58-1
Formula
MW	1505.46
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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