EB-TCIP Datasheet DC Chemicals

Description	EB-TCIP (BAK-04-212) is a bivalent molecule comprised of AP1867 and BI-3812. EB-TCIP can form a reversible ternary complex between FKBPF36V and BCL6BTB. EB-TCIP recruits FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, leading to rapid expression of BCL6 target genes (eg: SOCS2 and CXCL11). EWS/FLI1 is a fusion transcription factors in Ewing sarcoma. EB-TCIP can be used for research of deregulated transcription in cancer.
Cat.No	DC77493
Name	EB-TCIP

Chemical Properties

CAS
Formula	C68H86CLN9O15
MW	1304.91
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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