EN1033 Datasheet DC Chemicals

Description	EN1033 is a covalent Immune regulatory transcription factor 5/8 (IRF5/8) degrader. EN1033 destabilizes and degrades IRF5 and IRF8 by covalently targeting cysteine residues C28 and C223, respectively, inhibiting their pro-inflammatory transcriptional activity, such as the reduced mRNA level of IL1A, IL1B and CCL2. EN1033 can be used for autoimmune and inflammatory diseases research.
Cat.No	DC78116
Name	EN1033

Chemical Properties

CAS	2193367-28-9
Formula	C15H18N2O
MW	242.32
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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