NEP108 Datasheet DC Chemicals
Description NEP108 is a GID4 E3 ligase-based BRD4 PROTAC degrader, with its DC50 value approximately 3.8 μM. NEP108 has a strong affinity for GID4, with a KD value of 0.22 μM, and the KD value of its trimeric complex is 2.85 μM. NEP108 can be used for cancer research. (Pink: BRD4 ligand ; Blue: Ligands for E3 Ligase ligand ; Black: linker).
Cat.No DC81142
Name NEP108

Chemical Properties

CAS 301232-45-1
Formula C15H27NO4
MW 285.38
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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