KRAS-IN-48 free base Datasheet DC Chemicals

Description	KRAS-IN-48 free base (Compound 1-01) is a mutant KRAS inhibitor, with Kd values of 2.58 nM and 5.49 μM for KRAS G12D and KRAS G12V, respectively. KRAS-IN-48 free base affects pERK expression in cells harboring KRAS G12D and KRAS G12V mutations, with IC50 values of 1.1 μM and 1.51 μM, respectively. KRAS-IN-48 free base can be used in the research of cancer.
Cat.No	DC80918
Name	KRAS-IN-48 free base

Chemical Properties

CAS	3059497-30-9
Formula	C28H29FN4O4
MW	504.55
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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