GLPG4471 Datasheet DC Chemicals

Description	GLPG4471 is a selective and orally active IRAK4 inhibitor with an IC50 of 1.7 nM. GLPG4471 exhibits potent inhibition of cytokine (TNFα and IFNα) secretion in cellular and whole blood phenotypic assays. GLPG4471 displays significant activity in a mouse model of collagen-induced arthritis. GLPG4471 can be used for the study of arthritis.
Cat.No	DC79857
Name	GLPG4471

Chemical Properties

CAS	2499855-36-4
Formula	C22H26N4O4
MW	410.47
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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