KMG-1068 Datasheet DC Chemicals
Description KMG-1068 (Compound 4a), a molecular glue, is a GSPT1/2 degrader. KMG-1068 effectively induces the CRBN-dependent degradation of GSPT1/2 by binding to the IMiD binding site on CRBN, facilitating the formation of a ternary complex with GSPT1/2. KMG-1068 is promising for research of cancers.
Cat.No DC77547
Name KMG-1068

Chemical Properties

CAS
Formula C21H22N4O4S
MW 426.49
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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