ATOX1-IN-1 Datasheet DC Chemicals
Description ATOX1-IN-1 is an inhibitor of ATOX1 (a copper chaperone protein) with a Kd value of 12.5 μM. ATOX1-IN-1 induces intracellular copper accumulation, increases the level of DNA methylation in the NOTCH1 promoter region, and inhibits the NOTCH1/HES1 signaling pathway. ATOX1-IN-1 enhances the sensitivity of hepatocellular carcinoma cells to Cisplatin. ATOX1-IN-1 can be used in hepatocellular carcinoma-related research.
Cat.No DC80272
Name ATOX1-IN-1

Chemical Properties

CAS 918870-43-6
Formula C24H26N6O3
MW 446.51
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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