PROTAC HDAC3 degrader-1 Datasheet DC Chemicals

Description	PROTAC HDAC3 degrader-1 is a selective PROTAC degrader targeting HDAC3 with a DC50 of 30.73 nM. PROTAC HDAC3 degrader-1 induces degradation of HDAC3 via the ubiquitin-proteasome system. PROTAC HDAC3 degrader-1 promotes apoptosis, induces DNA damage, and downregulates anti-apoptotic proteins Mcl-1 and Bcl-xL. PROTAC HDAC3 degrader-1 can be used for the research of acute myeloid leukemia. (Pink: HDAC3 ligand ; Blue: VHL ligand ; Black: linker).
Cat.No	DC81377
Name	PROTAC HDAC3 degrader-1

Chemical Properties

CAS	3104325-26-7
Formula	C18H18F2N6O3S
MW	436.44
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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