Mal-amide-PEG8-Val-Cit-PAB-PNP Datasheet DC Chemicals
Description Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker featuring a maleimide, a PEG spacer, a Val-Cit dipeptide, a PAB. and a PNP carbonate. Maleimide is a thiol-specific covalent linker which is used to label cysteine residues in proteins while the PNP group acts as a highly activated leaving group. Val-Cit linkers are cleaved by cytoplasmic peptidases.
Cat.No DC77579
Name Mal-amide-PEG8-Val-Cit-PAB-PNP

Chemical Properties

CAS 1964490-09-2
Formula C51H74N8O20
MW 1119.17
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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