MEL23 Datasheet DC Chemicals

Description	MEL23 is a MDM2 E3 ligase inhibitor that blocks the E3 ligase activity of the MDM2-MDMX complex. MEL23 inhibits Mdm2 and p53 ubiquitination in cells, reduce viability of cells with wild-type p53. MEL23 stabilizes MDM2 via a mechanism independent of p53 transcription.
Cat.No	DC77599
Name	MEL23

Chemical Properties

CAS	642072-49-9
Formula	C19H22N4O3
MW	354.40
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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