Mirikizumab Biosimilar（Anti-IL-23 Reference Antibody） Datasheet DC Chemicals
Description Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 (IL-23). Mirikizumab binds to human and monkey IL-23 with high affinity, with Kd values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease.
Cat.No A249
Name Mirikizumab Biosimilar（Anti-IL-23 Reference Antibody）

Chemical Properties

CAS 1884201-71-1
Synonyms Mirikizumab;LY 3074828;3: PN: WO2017049035 SEQID: 8 claimed protein
pH value Corresponds to reference standard: PASS
Non-reduced CE-SDS >95%
SEC-HPLC >95%
Isoelectric Point Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality Corresponds to reference standard: PASS
Peptide mapping Corresponds to reference standard: PASS
N-terminal sequence Corresponds to reference standard: PASS

References

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