PROTAC EML4-ALK Degrader-2 Datasheet DC Chemicals

Description	PROTAC EML4-ALK Degrader-2 is an EML4-ALK PROTAC degrader. PROTAC EML4-ALK Degrader-2 shows potent selective inhibitory activity to ALK with an IC50 of 1.6 nM. PROTAC EML4-ALK exhibits selectivity over IGF1R, INSR, FLT3, and FGFR2. PROTAC EML4-ALK Degrader-2 shows anti-cancer activities both in vitro and vivo. PROTAC EML4-ALK Degrader-2 can be used for non-small cell lung cancer (NSLC), liver lung and cervical cancer research. (Pink: EML4-ALK ligand ; Blue: Cereblon ligand ; Black: linker ).
Cat.No	DC81350
Name	PROTAC EML4-ALK Degrader-2

Chemical Properties

CAS	1202697-61-7
Formula	C14H21N3O9S3
MW	471.53
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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