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Nedisertib (Synonyms: Peposertib; M3814)

  Cat. No.:  DC70085   Featured
Chemical Structure
1637542-33-6
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More than 5000 active chemicals with high quality for research!
Field of application
Nedisertib (M3814, MSC2490484A) is a highly potent, selective, orally bioavailable inhibitor of DNA-PK.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1637542-33-6
Chemical Name: Nedisertib
Synonyms: M 3814;M3814;MSC-2490484A;MSC2490484A;MSC 2490484A
SMILES: COC1=CC=C([C@@H](O)C2=CC(C3=C(C=CC(N4CCOCC4)=C5)C5=NC=N3)=C(F)C=C2Cl)N=N1
Formula: C24H21ClFN5O3
M.Wt: 481.912
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC70085 Nedisertib (Synonyms: Peposertib; M3814) Nedisertib (M3814, MSC2490484A) is a highly potent, selective, orally bioavailable inhibitor of DNA-PK.
DC46491 BAY-8400 BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 81 nM. BAY-8400 shows synergistic activity of DNA-PK inhibition when combined with DNA damage inducing cancer therapy, like targeted alpha radiation.
DC3113 KU-0060648 KU 0060648 is a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM); with 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases.
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