NS3736 Datasheet DC Chemicals
Description NS3736 is an orally effective chloride channel inhibitor that can be used for the research of osteoporosis. NS3736 targets the CIC-7 channel in osteocytes, blocks osteoclast acidification and resorption in vitro, with IC50=30 μM. In a rat model of ovariectomy-induced osteoporosis, NS3736 can enhance bone strength and bone density.
Cat.No DC76746
Name NS3736

Chemical Properties

CAS 265646-94-4
Formula C15H9BRCLF3N6O
MW 461.62
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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