NVP-BQS481 Datasheet DC Chemicals

Description	NVP-BQS481 (Compound 1) is a selective Kinesin spindle protein-5 (Eg5) inhibitor with an IC50< 0.5 nM. NVP-BQS481 has significant antimitotic and antitumor activity (IC50: 0.0.9 nM for SK-OV-3ip cells). NVP-BQS481 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs).
Cat.No	DC78650
Name	NVP-BQS481

Chemical Properties

CAS	1161925-41-2
Formula	C27H33F3N4O2
MW	502.57
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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