PBD dimer-4 Datasheet DC Chemicals
Description PBD dimer-4 (Compound 7) is a C1-subsitituted PBD dimer. PBD dimer-4 has high DNA-binding affinity, DNA cross-linking ability and potent cytotoxicity against MDA-MB-231 cells (IC50: 236 nM). PBD dimer-4 can be used as a payload of ADC Loncastuximab tesirine to treat several different cancer types.
Cat.No DC77915
Name PBD dimer-4

Chemical Properties

CAS 1821339-88-1
Formula C31H36N4O8
MW 592.64
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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