PF-06658607 Datasheet DC Chemicals
Description PF-06658607 is an alkynylated irreversible Brutons tyrosine kinase (BTK) inhibitor that covalently reacts with active site cysteines in the ATP-binding pocket. PF-06658607 can be used to detect "off "-targets for covalent kinase inhibitors in cancer cells. The alkyne moiety allows for azide-based detection probe via copper-catalyzed click chemistry.
Cat.No DC78115
Name PF-06658607

Chemical Properties

CAS 1621002-24-1
Formula C27H24N6O2
MW 464.52
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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