KG-FP-003 Datasheet DC Chemicals

Description	KG-FP-003 is a highly potent, selective, and durable TEAD PROTAC degrader (TEAD1 DC50 = 6 ± 4 nM, TEAD2 DC50 = 68 ± 15 nM, TEAD3 DC50 = 12 ± 5 nM, TEAD4 DC50 = 7 ± 5 nM). KG-FP-003 promotes ubiquitination and degradation of TEAD. KG-FP-003 exhibits anticancer activity against mesothelioma and ovarian cancer. (Pink: Ligands for Target Protein for PROTAC and TEAD ligand ; Blue: Ligands for E3 Ligase and Cereblon E3 ligase ligand; Black: linker).
Cat.No	DC80901
Name	KG-FP-003

Chemical Properties

CAS	2851986-77-9
Formula	C32H26FN9O2S
MW	619.67
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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