PNU 142300 Datasheet DC Chemicals
Description PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic Linezolid. NCB-0846 is an orally active, selective inhibitor for Wnt, that inhibits Traf2- and Nck-interacting kinase (TNIK) with an IC50 of 21 nM. NCB-0846 blocks TGF-β signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation.
Cat.No DC77678
Name PNU 142300

Chemical Properties

CAS 368891-69-4
Formula C16H20FN3O6
MW 369.34
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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