TSI-13-57 Datasheet DC Chemicals

Description	TSI-13-57 is a pan-TLR inhibitor (IC50: 2.7 μM, 6.03 μM, 7.37 μM, 6.38 μM for TLR9, TLR7, TLR2, TLR4, respectively). TSI-13-57 inhibits homodimerization of the TIR domains of MyD88. TSI-13-57 reduces systemic inflammatory responses in LPS-induced mice.
Cat.No	DC81684
Name	TSI-13-57

Chemical Properties

CAS	2242788-68-5
Formula	C18H19CL2N5O5
MW	456.28
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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