PVTX-321 Datasheet DC Chemicals

Description	PVTX-321 (Compound 16a) is an orally active estrogen receptor α (ERα) degrader. PVTX-321 can potently degrade ERα (DC50=0.15 nM in MCF-7 cells) and also has inhibitory activity against mutant ERα (IC50=59 nM). PVTX-321 is promising for research of ER+/HER2- breast cancer.
Cat.No	DC79808
Name	PVTX-321

Chemical Properties

CAS	3026004-38-3
Formula	C51H55FN4O6
MW	839
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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