(Rac)-CFT7455 Datasheet DC Chemicals

Description	(Rac)-CFT7455 is a potent, racemic small-molecule degrader of the zinc finger transcription factors IKZF1 (Ikaros) and IKZF3 (Aiolos), operating through ubiquitin-proteasome-mediated degradation. It demonstrates exceptional cellular potency, with a GI50 of 0.05 nM in NCI-H929.1 cells. As the racemic form of CFT7455, it retains the same anticancer activity by selectively targeting IKZF1/3 for proteasomal destruction.
Cat.No	DC71590
Name	(Rac)-CFT7455

Chemical Properties

CAS	2504233-68-3
Formula	C28H27N3O4
MW	469.53
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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