(S)-dHTC1 Datasheet DC Chemicals

Description	(S)-dHTC1 is a molecular glue degrader targeting the transcriptional co-activator ENL. (S)-dHTC1 binds the ligase with high affinity only after forming the ENL:dHTC1 complex with an IC50 value of 93 nM. (S)-dHTC1 degrades ENL in MV4;11 cells with a DC50 value of 26 nM. (S)-dHTC1 can be used for acute myeloid leukemia study.
Cat.No	DC77217
Name	(S)-dHTC1

Chemical Properties

CAS	3081383-46-9
Formula	C33H40N8O6S
MW	676.79
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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