EP4 receptor antagonist 8 Datasheet DC Chemicals

Description	EP4 receptor antagonist 8 is an orally active EP4 antagonist (human EP4 IC50 = 6.40 nM). EP4 receptor antagonist 8 significantly reduced paw and joint swelling, inflammatory cell infiltration, cartilage damage, pannus formation, and joint bone erosion in arthritis (AIA) mice in a dose-dependent manner. EP4 receptor antagonist 8 can be used for the study of inflammatory pain.
Cat.No	DC80616
Name	EP4 receptor antagonist 8

Chemical Properties

CAS	3008577-34-9
Formula	C29H25F2N5O5S
MW	593.6
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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