T2M-010 Datasheet DC Chemicals

Description	T2M-010 is a potent, brain-penetrant TREM2 agonist (Kd = 0.83 μM). T2M-010 activates receptor-proximal signaling, inducing SYK phosphorylation in TREM2-expressing cells, and promotes microglial phagocytosis. T2M-010 can be used for the study of protective microglial responses relevant to Alzheimer’s disease (AD).
Cat.No	DC78128
Name	T2M-010

Chemical Properties

CAS	364611-21-2
Formula	C19H17N3S
MW	319.42
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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