NEURL1B-IN-1 Datasheet DC Chemicals

Description	NEURL1B-IN-1 is a NEURL1B degrader with a Kd value of 46.2 nM. NEURL1B-IN-1 binds to Arg422 within the NHR2 domain of NEURL1B, triggers its autoubiquitination and proteasomal degradation, disrupts its interaction with DLL1, and attenuates the Notch signaling pathway. NEURL1B-IN-1 induces cell cycle arrest and apoptosis, and inhibits migration of hepatocellular carcinoma cells. NEURL1B-IN-1 is applicable to research related to hepatocellular carcinoma.
Cat.No	DC81144
Name	NEURL1B-IN-1

Chemical Properties

CAS	3046416-94-5
Formula	C12H9FN4
MW	228.23
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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