MS40 Datasheet DC Chemicals

Description	MS40 is a WDR5 PROTAC degrader (Kd = 125 nM). MS40 promotes the ubiquitination and degradation of WDR5. MS40-induced WDR5 degradation leads to the dissociation of the MLL/KMT2A complex from chromatin, resulting in decreased H3K4me2 levels. MS40 can be used in the study of primary leukemia.
Cat.No	DC81085
Name	MS40

Chemical Properties

CAS	2375043-73-3
Formula	C24H24F3NO4
MW	447.45
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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