THX6 Datasheet DC Chemicals

Description	THX6 is the activator for human mitochondrial protease ClpP with an EC50 of 1.18 μM. THX6 exhibits cytotoxicity in ONC201-resistant cell SU-DIPG-VI with IC50 of 0.13 μM. THX6 inhibits the expression of mitochondrial-related proteins (such as parkin, TFAM, NRF1, SDHA), leads to impaired mitochondrial function. THX6 affects the lipid metabolism in cell membran, and exhibits antitumor potential.
Cat.No	DC77769
Name	THX6

Chemical Properties

CAS
Formula	C22H18CL2N4O2
MW	441.31
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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