TK-684 Datasheet DC Chemicals

Description	TK-684 is a potent and selective allosteric SHP2 inhibitor with IC50 values of 2.1, ＞1000 nM for SHP2WT, SHP22PTP, respectively. TK-684 inhibits cell proliferation and induces apoptosis. TK-684 decreases the protein expression of p-AKT, p-ERK.
Cat.No	DC78435
Name	TK-684

Chemical Properties

CAS
Formula	C17H21CLN8OS
MW	420.92
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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