TNG462 Datasheet DC Chemicals
Description TNG462 is a potent and selective MTA-cooperative PRMT5 inhibitor. TNG462 has a PRMT5-MTA Ki < 300 fM, HAP1 MTAP-null cellular SDMA IC50 of 800 pM and viability GI50 of 4 nM, an average 45-fold selectivity against MTAP WT cells.
Cat.No DC65519
Name TNG462

Chemical Properties

CAS 2760483-96-1
Formula C28H36N6O2S
MW 520.689444541931
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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