ALK-IN-35 Datasheet DC Chemicals

Description	ALK-IN-35 is a ALK degrader with an IC50 of 0.74 nM. ALK-IN-35 inhibits ALK kinase activity, increases the solvent-accessible surface area of hydrophobic residues near the ALK binding pocket, promotes ALK to form a partially unfolded conformation, and induces proteasomal degradation of ALK. ALK-IN-35 inhibits cancer cell proliferation. ALK-IN-35 can be used in research related to non-small cell lung cancer.
Cat.No	DC80184
Name	ALK-IN-35

Chemical Properties

CAS	3105660-96-3
Formula	C107H139N25O28S
MW	2255.46
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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