VU6024578 Datasheet DC Chemicals

Description	VU6024578 (BI02982816) is a selective, orally active positive allosteric modulator (PAM) for metabotropic glutamate receptor (mGluR1), that activates human mGluR1 and rat mGluR1 with EC50 of 54 nM and 46 nM. VU6024578 exhibits antipsychotic activity in rats amphetamine-induced hyperactivity models and MK-801, and has anti-tumor activity.
Cat.No	DC76572
Name	VU6024578

Chemical Properties

CAS
Formula	C20H18CLN5O2
MW	395.84
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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