VVD-065 Datasheet DC Chemicals

Description	VVD-065 is a first-in-class NRF2 inhibitor that acts via an unprecedented allosteric molecular glue mechanism. VVD-065 specifically and covalently engages Cys151 on KEAP1, which in turn promotes KEAP1-CUL3 complex formation, leading to enhancement of NRF2 degradation.
Cat.No	DC60938
Name	VVD-065

Chemical Properties

CAS
Formula
MW
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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