ZDZ-553 Datasheet DC Chemicals
Description ZDZ-553 is an orally active STAT1 inhibitor with an IC50 value of 0.87 μM. ZDZ-553 modulates STAT1 signaling to affect downstream lipid metabolism and inflammatory pathways. ZDZ-553 attenuates hepatic steatosis in NASH mouse models. ZDZ-553 reduces inflammatory responses in NASH mouse models. ZDZ-553 exhibits a defined safety profile. ZDZ-553 can be used for the research of nonalcoholic steatohepatitis.
Cat.No DC81782
Name ZDZ-553

Chemical Properties

CAS 3113010-46-8
Formula C24H28F3N5O6S2
MW 603.63
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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